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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1A
All Species:
33.94
Human Site:
S112
Identified Species:
53.33
UniProt:
P10644
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10644
NP_002725.1
381
42982
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Chimpanzee
Pan troglodytes
XP_511647
260
29299
L20
R
S
L
R
E
C
E
L
Y
V
Q
K
H
N
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537577
381
43019
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBC7
381
43167
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Rat
Rattus norvegicus
P09456
381
43076
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
S357
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Chicken
Gallus gallus
Q5ZM91
382
43332
S113
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Frog
Xenopus laevis
NP_001085084
381
43157
S112
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Zebra Danio
Brachydanio rerio
NP_001017732
379
43009
S110
Y
T
E
E
D
A
A
S
Y
V
R
K
V
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
N107
V
T
E
E
D
A
T
N
Y
V
K
K
V
V
P
Honey Bee
Apis mellifera
XP_396167
372
41646
S120
Y
K
T
M
A
A
L
S
K
A
I
A
K
N
V
Nematode Worm
Caenorhab. elegans
P30625
366
41449
T109
V
I
P
K
D
D
A
T
R
R
S
L
E
S
A
Sea Urchin
Strong. purpuratus
Q26619
369
41770
K117
A
R
L
T
E
A
V
K
N
I
L
L
F
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
W159
Q
P
N
N
F
D
D
W
T
P
D
H
Y
K
E
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E118
P
K
T
A
E
Q
L
E
R
L
K
K
A
I
S
Conservation
Percent
Protein Identity:
100
68.2
N.A.
97.9
N.A.
96.8
97.3
N.A.
58.7
92.4
92.6
91.5
N.A.
71.3
74
57.7
39.3
Protein Similarity:
100
68.2
N.A.
98.1
N.A.
97.3
98.4
N.A.
60
96
95.8
95.8
N.A.
81.6
85.3
73.4
56.9
P-Site Identity:
100
20
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
20
13.3
6.6
P-Site Similarity:
100
40
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
86.6
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
34
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
74
60
0
0
7
0
7
7
0
14
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
14
7
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
60
60
20
0
7
7
0
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
7
7
0
0
60
7
% I
% Lys:
0
14
0
7
0
0
0
7
7
0
14
74
7
7
0
% K
% Leu:
0
0
14
0
0
0
14
7
0
7
7
14
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
0
7
7
0
0
0
0
14
0
% N
% Pro:
7
7
7
0
0
0
0
0
0
7
0
0
0
0
60
% P
% Gln:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
7
0
7
0
0
0
0
14
7
54
0
0
7
0
% R
% Ser:
0
7
0
0
0
0
0
60
0
0
7
0
0
7
7
% S
% Thr:
0
60
14
7
0
0
7
7
7
0
0
0
0
0
0
% T
% Val:
14
0
0
0
0
0
7
0
0
67
0
0
60
7
7
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
0
67
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _